INTERVENTIONAL CARDIOLOGY IN INFANTS AND
CHILDREN
(with special reference to developing countries)
Dr Mazeni Alwi, MBBS (Queensland), MRCP (UK)
Introduction
The era of interventional cardiology in congenital heart disease was
ushered in 20 years ago by the publication of Kan’s report on the
first successful balloon dilatation of a stenotic pulmonary valve 1.
This provided the impetus to investigate and broaden the application
of balloon dilatation technique to other stenotic lesions such as
aortic valvar stenosis, coarctation of the aorta and peripheral
pulmonary stenosis2,3,4. Not long after, this was followed by
techniques to close shunts such as patent ductus arteriosus (PDA)
and atrial septal defect (ASD) 5,6.
Today, catheter-directed therapy is a major aspect of treatment in
congenital heart disease, with expanding indications and refinement
of existing techniques to make them more efficacious and safe 7,8,9.
This more or less parallels the development in paediatric cardiac
surgery. As more complex lesions become amenable to treatment with
at least reasonable mid-term outcome, increasingly catheter-based
therapy converge with surgery as a combined multi-stage approach to
management (9).
Traditionally cardiac catheterization has been regarded as the gold
standard of diagnosis in congenital heart disease. Anatomical
abnormalities are delineated by angiocardiography and the
haemodynamic derangements consequent to these aberrations can be
determined by measurement of flow and pressure abnormalities, and
quantification of shunts and vascular resistances.
Correspondence: Dr Mazeni Alwi, Consultant Paediatric
Cardiologist, National Heart Institute, 145, Jalan Tun Razak, 40500
Kuala Lumpur, Malaysia
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